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COLD SPRING HARBOR ASIA CONFERENCES


PRECISION CANCER BIOLOGY: FROM TARGETED TO IMMUNE THERAPIES

Presenting Author

Abstract Title

Talk/Poster

Aburatani, Hiroyuki

Genomic classification of gastric cancer for treatment selection

talk

Allison, James

Immune checkpoint blockade in cancer therapy—New insights and opportunities, and prospects for cures

talk

Bai, Fan

Genomic comparison of esophageal squamous cell carcinoma and its precursor lesions by multi-region whole exome sequencing

talk

Cao, Ying

Cancer cell terminal differentiation discloses the nature of tumorigenesis—An uncontrolled neural specification/development

talk

Chen, Jun-Jie

Src kinase inhibitor dasatinib sensitized TRAIL-mediated apoptosis through regulation of c-FLIP expression in human cancer cells

poster

Chen, Lei

A biomolecule counter for rare mutant DNA in blood

poster

cheng, songtao

Etomoxir induces cell cycle arrest and inhibits growth and migration of human bladder cancer cells.

poster

Cheng, Yabin

The role of Eyes Absent gene (EYA1) in melanoma pathogenesis and progression

talk

Chu, Tinyi

Chromatin run-on reveals nascent RNAs that differentiate normal and malignant brain tissue

poster

De Sauvage, Frederic

Targeting intestinal stem cells in cancer

talk

Dong, Chen

Understanding and modulating tumor microenvironment

talk

Fu, Yang-Xin

Targeted therapies that bridge innate and adaptive immunity

talk

Gajewski, Thomas

Tumor and host pathways regulating anti-tumor immunity and immunotherapy efficacy

talk

Gong, Jia-nan

Targeting the pro-survival BCL2 proteins with BH3 mimetic compounds for treating multiple myeloma

poster

Greenberg, Philip

Engineering T cells to eradicate tumors in the age of synthetic biology

talk

Guo, Xinyi

Global characterization of T cells in non-small cell lung cancer by single-cell sequencing

poster

He, Yaowu

CUB domain-containing protein 1 mediates β-catenin localization in colorectal cancer

talk

Ji, Hongbin

Phenotypic transition contributes to small cell lung carcinoma metastasis through TAZ down-regulation

talk

Ji, Qingzhou

High specificity and enhanced integration efficiency CRISPR/Cas9 systems for precise genome editing

talk

Kakimi, Kazuhiro

An immunogram for the cancer-immunity cycle—Towards personalized immunotherapy

talk

Karin, Michael

Immune control of liver tumorigenesis – basic concepts and implications for treatment

talk

Kawakami, Yutaka

Heterogeneity in the tumor-immune-microenvironments in human cancers and its personalized modulation

talk

Kim, Hyekang

C14ORF1 as a novel diagnostic and therapeutic mAb targeting pancreatic cancer stem cells

poster

Kuchroo, Vijay

IL-27 drives a transcriptional program that sets the stage for T cell dysfunction

talk

Li, Bo

Widespread B cell clonal expansions and related mechanisms of immune evasions in human cancers

talk

Li, Jing

B7H3 and B7S1 as promising candidate targets for immunotherapy of HCC

talk

Li, Wei

Drivers of endocrine resistance and synthetic lethal vulnerabilities in breast cancer

talk

Li, Yongmei

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation

talk

Lin, Kui

AKTing with precision—A journey from bench to bedside for the development of selective AKT inhibitors in cancer

talk

Liu, Pei

Knocking down a novel long noncoding RNA in neuroblastoma causes complete tumor regression

talk

Liu, Song

Systematic identification of regulatory variants associated with cancer risk

poster

Liu, Xiaole Shirle

Inference of gene signatures associated with response and resistance to targeted and immunotherapies

talk

Luan, Haitao

Loss of CHIP/STUB1 ubiquitin ligase in breast cancer unleashes an invasion program mediated by MZF1-cathepsin axis

poster

Mak, Tak

Beyond targeting oncogenes—Emerging anti-cancer strategies

talk

Miyano, Satoru

Supercomputer challenges for cancer genomics and TCR data analysis

talk

Nakagawa, Hidewaki

Cancer whole genome sequencing for precision oncology and cancer immunology

talk

Ouyang, Wenjun

Engage and enhance the functions of T cells in cancer immunotherapies

talk

Qian, Kaiyu

Capsaicin suppresses cell proliferation, induces cell cycle arrest and ROS production in bladder cancer cells through FOXO3a-mediated pathways

poster

Rasko, John

Manufacturing, regulatory and logistical challenges in clinical cell and gene therapies

talk

Ren, Xianwen

Inferring cellular signaling networks based on single-cell RNA-seq data

poster

Seshagiri, Somasekar

Targetable activating Her2 transmembrane domain mutations in human cancers

talk

Sharma, Padmanee

From the clinic to the lab—Investigating response and resistance mechanisms to immune checkpoint therapy

talk

Sharpe, Arlene

Biology of PD-1 checkpoint blockade

talk

Shibata, Tatsuhiro

Intersection of genome and immunological microenvironments in human hepatobiliaty cancer

talk

Shih, Hsin-An

PHRF1 promotes migration and invasion by regulating ZEB1 transcription in lung cancer

poster

Shivdasani, Ramesh

Intestinal stem cell plasticity and its chromatin basis

talk

SUN, WEI

A comprehensive function analysis of LMO2 in different breast cancer subtypes

poster

Tan, Patrick

Genomic and epigenomic profiles of Asian endemic cancers

talk

Tang, Wai Ying Yvonne

Plasticity of mammary epithelial cells following EGF withdrawal or EGFR inhibition

poster

Wang, Gang

PHLDA3 is a novel tumor suppressor of castration resistant prostate cancer

poster

Wang, Jiashi

Highly efficient double-stranded molecular tagging and consensus read reconstruction strategy enhances accuracy of ultra-low frequency mutation detection

poster

Wang, Kai

Inhibition of p21 activated kinases enhances chemo-therapeutic effects of multiple reagents on patient’s derived pancreatic cancer cell lines

poster

Wang, Weili

Keys to accelerated production of the right protein from the right cells

poster

WANG, Yuliang

Nuclear receptor LRH-1 plays a regulatory role in human prostate cancer stem cell maintenance

talk

WANG, ZHU

Prostate cancer stem cells and castration-resistant prostate cancer cells exhibit distinct expression patterns of nuclear receptors

poster

Wu, Chong

The spleen mediates a distinct hematopoietic stem/progenitor cell response to support the tumor-promoting myelopoiesis

poster

Wu, Hong

T-ALL leukemia stem cell fate is epigenetically controlled by the master regulator PU.1

talk

xiong, yaoyi

Decreased KNSTRN inhibits activities and induces apoptosis of bladder cancer cells via PI3K/AKT pathway

poster

Yuan, Bin

A phosphotyrosine switch controls antitumor activity of estrogen receptor β

poster

Yuan, Hai-Xin

Acetylation accumulates PFKFB3 in the cytoplasm to promote glycolysis and protects cells from apoptosis induced by cisplatin

poster

Yuan, Lushun

Down-regulation of LAPTM4B suppresses cell proliferation and migration, as well as induces cell cycle arrest at G0/G1 phase of bladder cancer cells

poster

Zang, Chongzhi

Functional transcription factor prediction using BART

poster

Zang, Xingxing

New immune checkpoint pathways—HHLA2 and its receptors including TMIGD2

talk

Zhang, Chengcheng (Alec)

ITIM receptors—Immune checkpoint proteins and tumor supporting factors

talk

Zhang, Xiaowen

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

poster

Zhang, Zemin

Single cell analysis of tumor microenvironment reveals distinct patterns of clonal expansion and functional states of immune cells

talk

Zheng, Pan

Searching for better and safer anti-CTLA4 antibody for cancer immunotherapy

talk

Zhou, Jie

Neoantigens derived from six recurrently mutated genes as ideal potential targets for further immunotherapy against gastric cancer

poster

Zhu, Ping

Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

talk

 

 

 

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